Effect of PPAR inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension
نویسندگان
چکیده
Jing Tian, Anita Smith, John Nechtman, Robert Podolsky, Saurabh Aggarwal, Connie Snead, Sanjiv Kumar, Manal Elgaish, Peter Oishi, Agnes Göerlach, Sohrab Fratz, John Hess, John D. Catravas, Alexander. D. Verin, Jeffrey R. Fineman, Jin-Xiong She, and Stephen M. Black Pulmonary Vascular Disease Program, Vascular Biology Center, Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, Georgia; Paediatric Cardiology, German Heart Centre, Munich, Germany; and Pediatrics and The Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California
منابع مشابه
Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.
Peroxisome proliferator-activated receptor type gamma (PPARgamma) is a subgroup of the PPAR transcription factor family. Recent studies indicate that loss of PPARgamma is associated with the development of pulmonary hypertension (PH). We hypothesized that the endothelial dysfunction associated with PPARgamma inhibition may play an important role in the disease process by altering cellular gene ...
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تاریخ انتشار 2009